Join us for the 5th Annual Muddy River Marathon, May 3, 2025.  The course highlights many landmarks in Cape Girardeau including the Bill Emerson Bridge, Common Pleas Courthouse, Dalhousie Golf Course, Old St. Vincent's Church and more, as well as finishing along the Missouri Wall of Fame Mural.  The course is relatively flat utilizing roadways and paved trails.  We hope you will spend the evening in Cape and celebrate your accomplishment.  Proceeds benefit local non-profits who work to improve the health and wellbeing of those living in the region. Thanks to our sponsors and participants, we have been able to give over $70,000 to local non-profit's since the Muddy River Marathon's inception. In our fourth year we plan to continue expanding the beneficiaries around Southeast Missouri.